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A new ‘Pain Sensing’ gene discovered!

Researchers analysed the genetic make-up of 11 families across Europe and Asia affected by an inherited condition known as congenital insensitivity to pain (CIP). This enabled them to pinpoint the cause of the condition to variants of the gene PRDM12. Family members affected by CIP carried two copies of the variant; however, if they had only inherited one copy from their parents, they were unaffected. PRDM12 had previously been implicated in the modification of chromatin, a small molecule that attaches to our DNA and acts like a switch to turn genes on and off (an effect known as epigenetics). The researchers showed that all the genetic variants of PRDM12 in the CIP patients blocked the gene's function. The team looked at nerve biopsies taken from the patients to see what had gone wrong and found that particular pain-sensing neurons were absent. From these clinical features of the disease, the team predicted that there would be a block to the production of pain-sensing neur...

Hootsuite - A modern Social Media Management Tool

Hootsuite is a social media management system for brand management created by Ryan Holmes in 2008. The system’s user interface takes the form of a dashboard, and supports social network integrations for Twitter, Facebook, LinkedIn, Google+, Foursquare, MySpace, WordPress, TrendSpottr and Mixi. Additional integrations are available via Hootsuite’s App Directory, including Instagram, MailChimp, Reddit, Storify, Tumblr, Vimeo and YouTube. Based in Vancouver, Hootsuite has over 500 staff located in Vancouver, San Francisco, New York, Hong Kong, London, Sydney, Singapore, and other countries. The company operates on a freemium model and has over 10 million users in more than 175 countries. The service is commonly used to manage online brands and to submit messages to a variety of social media services, including Twitter, Facebook, Google+ and Mixi. Companies and organizations known to use Hootsuite include Facebook, PrintBindaas, the Obama administration, HBO, Martha Stewart Media, ...

Xiaomi Yi Action Camera - Unboxing, Setup & Hands On

In this video let's unbox Xiaomi's Yi Action Camera, set it up and spend some hands on time with it. Highlights of the the Yi Action Camera Ambarella A7LS DSP + 16MP Sony Exmor R BSI Back-illuminated CMOS Image Sensor 1080P 60/30FPS FHD Video Recording WiFi Connection for Android devices Aspheric HD Optical Glass Lens / F2.8 Large Aperture 155° Ultra Wide Angle High Performance 3-Axis G-sensor Small appearance, two colors available Multiple photo shooting modes: Single shot, Self-Timer, Time-lapse, Burst Shot Panasonic high efficiency Lipo Battery with low power consumption design, 1010mAh Battery Supports Micro SD cards up to 64GB maximum (Micro SD Class10+ recommended) Standard 1/4"-20 tripod mount compatible

Mahantesh Biradar

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